Heterogeneity of the human phosphocholine-specific B cell repertoire. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Heterogeneity of the human phosphocholine-specific B cell repertoire.

Dataset

identifier:	1812100
description:	epitope description:phosphocholine host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	6198388

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016340
landingPage:	http://www.iedb.org/assay/1812100

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	1984

Dimension

study type:	b cell assays
subject species:	Streptococcus pneumoniae

Person

fullName:	L D Stein N H Sigal

Data Type

method:	antigen inhibition

Study

name:	Heterogeneity of the human phosphocholine-specific B cell repertoire.
description:	The relative affinity of phosphocholine(PC)-specific mAbs from healthy donors to p-aminophenylphosphocholine (APPC) showed that the PC-specific antibodies are heterogeneous in its binding site, as some of them display higher affinities for APPC than for PC, some are similar, and some are more specific for PC than for APPC.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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