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Title: Deficiency of N-glycolylneuraminic acid and Galalpha1-3Galbeta1-4GlcNAc epitopes in xenogeneic cells attenuates cytotoxicity of human natural antibodies.
identifier: 1812173
description:
epitope description:N-glycoloyl-beta-neuraminic acid
host organism:Gallus gallus
antibody name:HU/Ch2-7
aggregation:
instance of dataset
availability:
available
primaryPublications: 21158945
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1021365
landingPage: http://www.iedb.org/assay/1812173
type:
Literature
publicationVenue:
Xenotransplantation
dates:
2010
study type: b cell assays
subject species: Mus musculus
fullName:
Nabin B Basnet
Kentaro Ide
Hiroyuki Tahara
Yuka Tanaka
Hideki Ohdan
method:
immuno staining
name:
Deficiency of N-glycolylneuraminic acid and Galalpha1-3Galbeta1-4GlcNAc epitopes in xenogeneic cells attenuates cytotoxicity of human natural antibodies.
description:
The epitope-specific mAb immunostained lung, heart and liver of C57BL/6J and of mice deficient of alpha1,3-galactosyltransferase mice. The epitope-specific mAb also recognized bone marrow cells, splenocytes and thymocytes derived from these mice as determined by FACS.

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