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identifier: 1812368
description:
epitope description:Y45, L49, R52, G53, A54, P55, G56, A57, Q58, I60, T61, Y62, R64
host organism:Mus musculus
antibody name:Fab
aggregation:
instance of dataset
availability:
available
primaryPublications: 15099749
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001556
landingPage: http://www.iedb.org/assay/1812368
type:
Literature
publicationVenue:
J Mol Biol
dates:
2004
study type: b cell assays
subject species: Streptomyces lividans
fullName:
Ming Zhou
Roderick MacKinnon
method:
x-ray crystallography
name:
A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution.
description:
The epitope residues are calculated from [PDB: 1S5H] at 4Å
distance.
The epitope of Fab on the KcsA potassium channel with mutation T75C, in the presence of 200 mM K+, was determined from the crystal structure of the complex. The C-terminal 35 amino acids of KcsA were removed by proteolysis.

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