Structural and thermodynamic properties of selective ion binding in a K+ channel. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Structural and thermodynamic properties of selective ion binding in a K+ channel.

Dataset

identifier:	1812573
description:	epitope description:Y45, L49, A50, R52, G53, A54, P55, G56, A57, Q58, I60, T61, Y62, P63, R64 host organism:Mus musculus antibody name:Fab
aggregation:	instance of dataset
availability:	available
primaryPublications:	17472437

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1019327
landingPage:	http://www.iedb.org/assay/1812573

Publication

type:	Literature
publicationVenue:	PLoS Biol
dates:	2007

Dimension

study type:	b cell assays
subject species:	Streptomyces lividans

Person

fullName:	Steve W Lockless Ming Zhou Roderick MacKinnon

Data Type

method:	x-ray crystallography

Study

name:	Structural and thermodynamic properties of selective ion binding in a K+ channel.
description:	The epitope residues are calculated from [PDB: 2ITC] at 4Å distance. In the epiotpe calculated from either [PDB: 2ITD] or [PDB:2NLJ] A50 and P63 residues are missed. The epitope of Fab on the KcsA potassium channel, in the presence of NaCl, was determined from the crystal structure of the complex. The C-terminal 35 amino acids of KcsA were removed by proteolysis.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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