| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019985 |
| landingPage: |
http://www.iedb.org/assay/1815501 |
| type: |
Literature
|
| publicationVenue: |
J Exp Med
|
| dates: |
1977
|
| study type: | b cell assays |
| subject species: |
| fullName: |
S K Pierce
N R Klinman
|
| method: |
radio immuno assay (RIA)
|
| name: |
Antibody-specific immunoregulation.
|
| description: |
If donor and recipient strains shared only genes within the H-2 complex and differed in all genes outside that complex, as in the BALB/c and B10.D2 combination, the frequency of DNP-specific primary B-cell responses was equivalent in Hy and DNP-Hy immunized recipients. Further, if donor and recipient strains were identical with the exception of genes which code for immunoglobulin heavy chains, as in the BALB/c and CB20 strain combination, the frequency of donor anti-DNP specific B-cell responses in DNP-Hy-primed recipients was equivalent to the frequency in Hy-primed recipients. The same was true using BSA as carrier.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |