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identifier: 1815501
description:
epitope description:2,4-dinitrophenol
host organism:Mus musculus B10.D2
aggregation:
instance of dataset
availability:
available
primaryPublications: 301552
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019985
landingPage: http://www.iedb.org/assay/1815501
type:
Literature
publicationVenue:
J Exp Med
dates:
1977
study type: b cell assays
subject species:
fullName:
S K Pierce
N R Klinman
method:
radio immuno assay (RIA)
name:
Antibody-specific immunoregulation.
description:
If donor and recipient strains shared only genes within the H-2 complex and differed in all genes outside that complex, as in the BALB/c and B10.D2 combination, the frequency of DNP-specific primary B-cell responses was equivalent in Hy and DNP-Hy immunized recipients. Further, if donor and recipient strains were identical with the exception of genes which code for immunoglobulin heavy chains, as in the BALB/c and CB20 strain combination, the frequency of donor anti-DNP specific B-cell responses in DNP-Hy-primed recipients was equivalent to the frequency in Hy-primed recipients. The same was true using BSA as carrier.

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