Human monoclonal autoantibody fragments from combinatorial antibody libraries directed to the U1snRNP associated U1C protein; epitope mapping, immunolocalization and V-gene usage.

Title:

Human monoclonal autoantibody fragments from combinatorial antibody libraries directed to the U1snRNP associated U1C protein; epitope mapping, immunolocalization and V-gene usage.

Dataset

identifier:	1813076
description:	epitope description:GGPPMMPMMGPPPPGMMPVGPAPGMRPPM antigen name:U1 small nuclear ribonucleoprotein C host organism:Homo sapiens antibody name:K11, K15, K36
aggregation:	instance of dataset
availability:	available
primaryPublications:	10068039

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006963
landingPage:	http://www.iedb.org/assay/1813076

Publication

type:	Literature
publicationVenue:	Mol Immunol
dates:	1998

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	R M Hoet J M Raats R de Wildt H Dumortier S Muller F van den Hoogen W J van Venrooij

Data Type

method:	ELISA

Study

name:	Human monoclonal autoantibody fragments from combinatorial antibody libraries directed to the U1snRNP associated U1C protein; epitope mapping, immunolocalization and V-gene usage.
description:	The epitope sequence is found in Sillekens PT et al. Nucleic Acids Res. 1988 Sep 12 16(17):8307-21 [PMID: 2971157]. The epitope-specific antibody fragments bind to U1C in ELISA and Western blot.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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