Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies.

Title:

Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies.

identifier:	1813087
description:	epitope description:alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	12199866

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Marit Saethre Una Ø Sø lvik Guttorm Haraldsen Arnt E Fiane Eva Boretti Erik Thorsby Jeffrey L Platt Tom E Mollnes

method:	ELISA

name:	Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies.
description:	There was a great interindividual variation of anti-Gal IgM antibodies in the sera from 80 blood donors, which ranged from 2 to 87 μg/ml. There was a significantly higher concentration of IgM anti-Gal in females than in males. Furthermore, females aged 20–29 had significantly higher concentration compared with females aged 40–49 and 50–59. Females aged 20–29 and 30–39 also had a significantly higher concentration than the corresponding male groups. There were no age differences in the male group.

name:	iedb
homePage:	http://www.iedb.org

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