| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019328 |
| landingPage: |
http://www.iedb.org/assay/1813468 |
| type: |
Literature
|
| publicationVenue: |
J Mol Biol
|
| dates: |
2007
|
| study type: | b cell assays |
| subject species: | Streptomyces lividans |
| fullName: |
Sarah Yohannan
Yue Hu
Yufeng Zhou
|
| method: |
x-ray crystallography
|
| name: |
Crystallographic study of the tetrabutylammonium block to the KcsA K+ channel.
|
| description: |
The epitope residues are calculated from the PDB [PDB: 2DWD] structure as the antigen residues at 4 Å
distance from the antibody.
The epitope of Fab fragment on the KcsA potassium channel, in the presence of channel blocker tetrabutylammonium (TBA) and Tl+, was determined from the crystal structure of the complex. The C-terminal 35 amino acids of KcsA were removed by proteolysis.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |