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identifier: 1813468
description:
epitope description:Y45, L49, R52, G53, A54, P55, G56, A57, Q58, I60, T61, Y62, P63, R64
host organism:Mus musculus
antibody name:Fab
aggregation:
instance of dataset
availability:
available
primaryPublications: 17196615
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019328
landingPage: http://www.iedb.org/assay/1813468
type:
Literature
publicationVenue:
J Mol Biol
dates:
2007
study type: b cell assays
subject species: Streptomyces lividans
fullName:
Sarah Yohannan
Yue Hu
Yufeng Zhou
method:
x-ray crystallography
name:
Crystallographic study of the tetrabutylammonium block to the KcsA K+ channel.
description:
The epitope residues are calculated from the PDB [PDB: 2DWD] structure as the antigen residues at 4 Å
distance from the antibody.
The epitope of Fab fragment on the KcsA potassium channel, in the presence of channel blocker tetrabutylammonium (TBA) and Tl+, was determined from the crystal structure of the complex. The C-terminal 35 amino acids of KcsA were removed by proteolysis.

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