Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.

Title:

Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.

identifier:	1813783
description:	epitope description:E33, R35, I36, F37, P38, K39, M41, D42, Q47, K48, V49, D50, V52, E54, L56, G57, K111, S141 antigen name:T-cell surface glycoprotein CD8 alpha chain host organism:Rattus norvegicus antibody name:YTS 105.18
aggregation:	instance of dataset
availability:	available
primaryPublications:	16530222

study type:	b cell assays
subject species:	Mus musculus

fullName:	D A Shore L R A Dwek P M Rudd I A Wilson

method:	x-ray crystallography

name:	Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.
description:	The epitope residues are calculated from the PDB structure as the antigen residues at 4 Å distance from the antibody. The epitope of YTS 105.18 on the CD8alphaalpha dimer was determined from the crystal structure of the complex, solved by molecular replacement.

name:	iedb
homePage:	http://www.iedb.org

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