Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity.

Title:

Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity.

Dataset

identifier:	1814834
description:	epitope description:PPPGMRPP antigen name:Small nuclear ribonucleoprotein-associated protein N host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	7530756

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006972
landingPage:	http://www.iedb.org/assay/1814834

Publication

type:	Literature
publicationVenue:	J Exp Med
dates:	1995

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	J A James R H Scofield J B Harley

Data Type

method:	immunoprecipitation

Study

name:	Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity.
description:	Rabbit antiserum to the epitope immunoprecipitated U1, U2, U4/6, and U5 RNAs from Hela cell extracts, Western Blot was also positive.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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