Anti-Gal antibodies in humans and 1, 3alpha-galactosyltransferase knock-out mice. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Anti-Gal antibodies in humans and 1, 3alpha-galactosyltransferase knock-out mice.

Dataset

identifier:	1814851
description:	epitope description:alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group host organism:Mus musculus alpha-galactosyl transferase null
aggregation:	instance of dataset
availability:	available
primaryPublications:	10910282

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1021401
landingPage:	http://www.iedb.org/assay/1814851

Publication

type:	Literature
publicationVenue:	Transplantation
dates:	2000

Dimension

study type:	b cell assays
subject species:	Oryctolagus cuniculus

Person

fullName:	T R Chiang L Fanget R Gregory Y D L Ardiet L Gao C Meschter A P Kozikowski R Buelow W M Vuist

Data Type

method:	ELISA

Study

name:	Anti-Gal antibodies in humans and 1, 3alpha-galactosyltransferase knock-out mice.
description:	Epitope-immunization induced high titer of epitope-specific IgG and caused hyperacute rejection of epitope-positive heart transplant in recipient mice. Immunohistology of the rejected heart showed similar results.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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