Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by a Galalpha1-3Galbeta1-4betaGlc-X immunoaffinity column.

Title:

Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by a Galalpha1-3Galbeta1-4betaGlc-X immunoaffinity column.

Dataset

identifier:	1814924
description:	epitope description:alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	9458010

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1021442
landingPage:	http://www.iedb.org/assay/1814924

Publication

type:	Literature
publicationVenue:	Transplantation
dates:	1998

Dimension

study type:	b cell assays
subject species:	Sus scrofa

Person

fullName:	Y Xu T Sablinski P Gianello M Bailin R Monroy T Kozlowski M Awwad D K Cooper D H Sachs

Data Type

method:	antigen inhibition

Study

name:	Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by a Galalpha1-3Galbeta1-4betaGlc-X immunoaffinity column.
description:	Preabsorption with the epitope inhibited binding of human sera to itself and to pig PBMCs. Preabsorption also inhibited cytotoxicity of human sera against pig cells. The epitope was also bound by human sera directly in flow cytometry.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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