| identifier: | 1815021 |
| description: |
epitope description:beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1->4)-[alpha-D-GlcpNAc-(1->2)-3-PEA-L-alpha-D-Hepp-(1->3)]-L-alpha-D-Hepp-(1->5)-alpha-Kdo
antigen name:lipooligosaccharide
host organism:Oryctolagus cuniculus ELCO
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
1900063 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1008268 |
| landingPage: |
http://www.iedb.org/assay/1815021 |
| type: |
Literature
|
| publicationVenue: |
Infect Immun
|
| dates: |
1991
|
| study type: | b cell assays |
| subject species: | Neisseria meningitidis |
| fullName: |
A F Verheul
A K Braat
J M Leenhouts
P Hoogerhout
J T Poolman
H Snippe
J Verhoef
|
| method: |
antigen inhibition
|
| name: |
Preparation, characterization, and immunogenicity of meningococcal immunotype L2 and L3,7,9 phosphoethanolamine group-containing oligosaccharide-protein conjugates.
|
| description: |
The epitope-TT conjugate is able to induce anti-LOS IgG responses and the free oligosaccharide inhibits the reactivity to LOS in competitive ELISA. Partially dephosphorylated oligosaccharide has a similar or higher inhibitory capacitiy. The presence of QuilA as an adjuvant probably influenced the fine specificity of the elicited antibodies, but not its titer.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |