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identifier: 1815138
description:
epitope description:FSPAYLRDAALK
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 20416126
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1021648
landingPage: http://www.iedb.org/assay/1815138
type:
Literature
publicationVenue:
J Helminthol
dates:
2011
study type: b cell assays
subject species:
fullName:
A Villa-Mancera
H Quiroz-Romero
D Correa
R A Alonso
method:
in vivo assay
name:
Proteolytic activity in Fasciola hepatica is reduced by the administration of cathepsin L mimotopes.
description:
Of the ten immunized mice, 3 showed 0 flukes 8 weeks after infection. The overall reduction of fluke burden was 45.83%. In situ zymography of liver sections showed reduced gelatin degradation (72.58%).

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