| Title: | Proteolytic activity in Fasciola hepatica is reduced by the administration of cathepsin L mimotopes. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1021648 |
| landingPage: |
http://www.iedb.org/assay/1815138 |
| type: |
Literature
|
| publicationVenue: |
J Helminthol
|
| dates: |
2011
|
| study type: | b cell assays |
| subject species: |
| fullName: |
A Villa-Mancera
H Quiroz-Romero
D Correa
R A Alonso
|
| method: |
in vivo assay
|
| name: |
Proteolytic activity in Fasciola hepatica is reduced by the administration of cathepsin L mimotopes.
|
| description: |
Of the ten immunized mice, 3 showed 0 flukes 8 weeks after infection. The overall reduction of fluke burden was 45.83%. In situ zymography of liver sections showed reduced gelatin degradation (72.58%).
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |