Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1011496 |
| landingPage: |
http://www.iedb.org/assay/1815342 |
| type: |
Literature
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| publicationVenue: |
J Exp Med
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| dates: |
1995
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| study type: | b cell assays |
| subject species: | Murine leukemia virus |
| fullName: |
R P Rother
W L Fodor
J P Springhorn
C W Birks
E Setter
M S Sandrin
S P Squinto
S A Rollins
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| method: |
biological activity
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| name: |
A novel mechanism of retrovirus inactivation in human serum mediated by anti-alpha-galactosyl natural antibody.
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| description: |
Epitope-specific antibodies purified from normal human sera are able to induce inactivation of the virus and to lead to complement-mediated lysis of MLV-producing cell line PA317. Down-regulation of the epitope expression on the cell line and, subsequently, on the retroviral particles lead to enhanced survival.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
