Epitope mapping of HLA-B27 and HLA-B7 antigens by using intradomain recombinants. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Epitope mapping of HLA-B27 and HLA-B7 antigens by using intradomain recombinants.

Dataset

identifier:	1816347
description:	epitope description:D101, T104 antigen name:HLA class I histocompatibility antigen, B-27 alpha chain host organism:Mus musculus C57BL/6 X BALB/c antibody name:TM-1
aggregation:	instance of dataset
availability:	available
primaryPublications:	2459214

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1020252
landingPage:	http://www.iedb.org/assay/1816347

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	1988

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	A Toubert C Raffoux J Boretto J Sire R Sodoyer S R Thurau B Amor J Colombani F A Lemonnier B R Jordan

Data Type

method:	radio immuno assay (RIA)

Study

name:	Epitope mapping of HLA-B27 and HLA-B7 antigens by using intradomain recombinants.
description:	The epitope was deduced. It was deduced that the anti-HLA-B27 mAb TM-1 recognizes one or both of the epitopic residues based on loss of reactivity with HLA-B7 and -B27 hybrid molecules with D77S and T80N substitutions and retained reactivity after substitution at other positions.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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