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identifier: 1816487
description:
epitope description:QRPVKELAFPGSSRE
antigen name:Len c 1
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 20816193
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1020784
landingPage: http://www.iedb.org/assay/1816487
type:
Literature
publicationVenue:
J Allergy Clin Immunol
dates:
2010
study type: b cell assays
subject species: Lens culinaris
fullName:
Andrea Vereda
Doerthe A Andreae
Jing Lin
Wayne G Shreffler
Maria Dolores Ibañ
ez
Javier Cuesta-Herranz
Ludmilla Bardina
Hugh A Sampson
method:
antigen inhibition
name:
Identification of IgE sequential epitopes of lentil (Len c 1) by means of peptide microarray immunoassay.
description:
The epitope was deduced.
Pooled allergic patients' serum IgE bound to the epitope in a scan of overlapping 15-mer peptides spanning the sequence of Len c 1. The epitope inhibited the binding of the pooled serum IgE to overlapping 15-mer peptides spanning the sequence of Len c 1 residues 373-399, which was deduced to contain an IgE epitope.

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