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Title: A broadly flavivirus cross-neutralizing monoclonal antibody that recognizes a novel epitope within the fusion loop of E protein.
identifier: 1816815
description:
epitope description:MVDRGWG
antigen name:Genome polyprotein
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 21264311
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1021593
landingPage: http://www.iedb.org/assay/1816815
type:
Literature
publicationVenue:
PLoS One
dates:
2011
study type: b cell assays
subject species: Dengue virus 2
fullName:
Yong-Qiang Deng
Jian-Xin Dai
Guang-Hui Ji
Tao Jiang
Hua-Jing Wang
Hai-ou Yang
Weng-Long Tan
Ran Liu
Man Yu
Bao-Xue Ge
Qing-Yu Zhu
E-De Qin
Ya-Jun Guo
Cheng-Feng Qin
method:
in vivo assay
name:
A broadly flavivirus cross-neutralizing monoclonal antibody that recognizes a novel epitope within the fusion loop of E protein.
description:
Prophylactic administration with a single dose of 200 ug mAb conferred 80% protection. Three of 8 mice survived one the mAb was administered one day after virus challenge.

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