Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1819646 |
| description: |
epitope description:U: E18, P19, S20, T55, L56, S57, D58, N60, I61, Q62; V: T7, L8, T9, E34, G35, I36, P37, D39, Q40, L71, R72, L73, R74, G75
antigen name:Ubiquitin-40S ribosomal protein S27a (UniProt:P62979)
host organism:Homo sapiens
antibody name:Apu2.16
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
18724939 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019698 |
| landingPage: |
http://www.iedb.org/assay/1819646 |
| type: |
Literature
|
| publicationVenue: |
Cell
|
| dates: |
2008
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Kim Newton
Marissa L Matsumoto
Ingrid E Wertz
Donald S Kirkpatrick
Jennie R Lill
Jenille Tan
Debra Dugger
Nathaniel Gordon
Sachdev S Sidhu
Frederic A Fellouse
Laszlo Komuves
Dorothy M French
Ronald E Ferrando
Cynthia Lam
Deanne Compaan
Christine Yu
Ivan Bosanac
Sarah G Hymowitz
Robert F Kelley
Vishva M Dixit
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
|
| description: |
The epitope residues are calculated from the PDB structure [PDB: 3DVN] as the antigen residues at 4 Å
distance from the antibody.
Epitope specific Apu2.16 Fab bound to K63-linked diubiquitin with KD = 92 nM compared to KD = 42000 nM for binding K48-linked diubiquitin.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
