Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans.

Title:

Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans.

identifier:	1819811
description:	epitope description:GLQYTPSWLVG host organism:Mus musculus BALB/c antibody name:2H1, 3E5, 14E1, 17E12, 18B7
aggregation:	instance of dataset
availability:	available
primaryPublications:	8760499

study type:	b cell assays
subject species:

fullName:	P Valadon G Nussbaum L F Boyd D H Margulies M D Scharff

method:	antigen inhibition

name:	Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans.
description:	The epitope inhibited the mAb (2H1) from binding to phage Φ514 and cryptococcal polysaccharide. A motif, (E)TPXWM/LM/L, was defined by screening phage display peptide libraries using the mAb (2H1). The epitope directly bound to the mAbs by ELISA.

name:	iedb
homePage:	http://www.iedb.org

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