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identifier: 1818697
description:
epitope description:2,4,6-trinitrophenyl group
host organism:Mus musculus BALB/cAnN
aggregation:
instance of dataset
availability:
available
primaryPublications: 301552
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019985
landingPage: http://www.iedb.org/assay/1818697
type:
Literature
publicationVenue:
J Exp Med
dates:
1977
study type: b cell assays
subject species:
fullName:
S K Pierce
N R Klinman
method:
radio immuno assay (RIA)
name:
Antibody-specific immunoregulation.
description:
The in vitro fragment culture system was employed to compare primary donor B-cell responses to TNP-Hy in TNP-Hy immunized recipients at various times after immunization to those of the same donor cell population transferred to recipients immunized with Hy alone. The number of TNP-specific primary B cells responding in fragment cultures derived from recipients immunized with TNP-Hy was significantly decreased as compared to the number of TNP-specific B cells responding in spleen fragments of recipients immunized with Hy alone.