Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1021452 |
| landingPage: |
http://www.iedb.org/assay/1818813 |
| type: |
Literature
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| publicationVenue: |
Transfusion
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| dates: |
1990
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| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
E Jaskiewicz
J J Moulds
K Kraemer
A S Goldstein
E Lisowska
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| method: |
antigen inhibition
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| name: |
Characterization of the epitope recognized by a monoclonal antibody highly specific for blood group M antigen.
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| description: |
The M glycoprotein was able to inhibit the binding of the epitope-specific mAb to plate-bound M glycoprotein. Direct binding was also shown by ELISA and Western blot. The epitope was identified by showing lack of binding to protein with the terminal Ser removed by Edman degradation. Desialylated protein also showed reduced biding, indicating that the sialic acid resides were also involved in the mAb binding.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
