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identifier: 1819103
description:
epitope description:LKGDDSAGEQEL
host organism:Mus musculus BALB/c
antibody name:MG96
aggregation:
instance of dataset
availability:
available
primaryPublications: 15780718
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002364
landingPage: http://www.iedb.org/assay/1819103
type:
Literature
publicationVenue:
Vaccine
dates:
2005
study type: b cell assays
subject species:
fullName:
Rhoel R Dinglasan
Johanna M Porter-Kelley
Uzma Alam
Abdu F Azad
method:
western blot
name:
Peptide mimics as surrogate immunogens of mosquito midgut carbohydrate malaria transmission blocking targets.
description:
This peptide mimics the glycan epitope recognized by the mAb MG96 in mosquito midgut. A screen of glycan array identified mannose-alpha(1&ndash
6) and N-acetyllactosamine glycans as principal components of the MG96 epitope but the complete oligosaccharide structure has not yet been confirmed.
The epitope as a fusion with the major bacterial flagellar protein (FliC) and thioredoxin (TrxA) was selected from a library of random peptides by the mAb MG96.

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