Partial characterization of the cross-reacting determinant, a carbohydrate epitope shared by decay accelerating factor and the variant surface glycoprotein of the African Trypanosoma brucei.

Title:

Partial characterization of the cross-reacting determinant, a carbohydrate epitope shared by decay accelerating factor and the variant surface glycoprotein of the African Trypanosoma brucei.

Dataset

identifier:	1821307
description:	epitope description:alpha-D-glucose host organism:Oryctolagus cuniculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	2450138

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003872
landingPage:	http://www.iedb.org/assay/1821307

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	1988

Dimension

study type:	b cell assays
subject species:

Person

fullName:	S Shak M A Davitz M L Wolinsky V Nussenzweig M J Turner A Gurnett

Data Type

method:	antigen inhibition (~ IC50)

Study

name:	Partial characterization of the cross-reacting determinant, a carbohydrate epitope shared by decay accelerating factor and the variant surface glycoprotein of the African Trypanosoma brucei.
description:	Inhibition by the epitope of affinity purified anti-CRD (cross-reacting determinant) antibodies reaction in RIA against the soluble form of decay accelerating factor (DFA-S), carrying a glycosyl phosphatidylinositol anchor was tested.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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