Antibodies against beta-fibrin synthetic peptides: a study of their association with the immunogenetic background and disease course of rheumatoid arthritis patients.

Title:

Antibodies against beta-fibrin synthetic peptides: a study of their association with the immunogenetic background and disease course of rheumatoid arthritis patients.

Dataset

identifier:	1821632
description:	epitope description:KYQISVNKYRGTAGNALMDGASQLMGENRT + CITR(R29) antigen name:Fibrinogen beta chain host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	21295379

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1021492
landingPage:	http://www.iedb.org/assay/1821632

Publication

type:	Literature
publicationVenue:	Eur J Med Chem
dates:	2011

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Isabel Haro Marí a J Gó mara a L Pé rez Odette Viñ as Guadalupe Ercilla José A Gó mez-Puerta Raimon Sanmartí

Data Type

method:	ELISA

Study

name:	Antibodies against beta-fibrin synthetic peptides: a study of their association with the immunogenetic background and disease course of rheumatoid arthritis patients.
description:	RA patients carrying HLA-DRB1 single or two shared epitopes (SE), QRRAA or QKRAA, displayed significantly higher level of anti-epitope antibody than patients with no SE. Anti-epitope positive status corresponded to mean Larsen scores measured by radiographic damage.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.