von Willebrand factor but not alpha-thrombin binding to platelet glycoprotein Ibalpha is influenced by the HPA-2 polymorphism.

Title:

von Willebrand factor but not alpha-thrombin binding to platelet glycoprotein Ibalpha is influenced by the HPA-2 polymorphism.

identifier:	1821936
description:	epitope description:DEGDTDLYDYYPEE antigen name:Platelet glycoprotein Ib alpha chain host organism:Mus musculus antibody name:27C11
aggregation:	instance of dataset
availability:	available
primaryPublications:	12775575

type:	Literature
publicationVenue:	Arterioscler Thromb Vasc Biol
dates:	2003

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Hans Ulrichts Karen Vanhoorelbeke Sandra Cauwenberghs Stephan Vauterin Hartmut Kroll Sentot Santoso Hans Deckmyn

method:	ELISA

name:	von Willebrand factor but not alpha-thrombin binding to platelet glycoprotein Ibalpha is influenced by the HPA-2 polymorphism.
description:	The epitope sequence was cited in Titani et al. Proc Natl Acad Sci U S A. 1987 Aug 84(16):5610-4 [PMID:3497398]. The mAb was shown to be epitope specific by being blocked by an epitope-specific mAb (LJ-Ib10) when binding to human platelets.

name:	iedb
homePage:	http://www.iedb.org

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