Use of RhD fusion protein expressed on K562 cell surface in the study of molecular basis for D antigenic epitopes.

Title:

Use of RhD fusion protein expressed on K562 cell surface in the study of molecular basis for D antigenic epitopes.

identifier:	1822256
description:	epitope description:DTVGA antigen name:Blood group Rh(D) polypeptide host organism:Homo sapiens antibody name:LOR15C9
aggregation:	instance of dataset
availability:	available
primaryPublications:	10026193

study type:	b cell assays
subject species:	Homo sapiens

fullName:	A Zhu S Haller H Li A Chaudhuri A Blancher K Suyama

method:	flow cytometry

name:	Use of RhD fusion protein expressed on K562 cell surface in the study of molecular basis for D antigenic epitopes.
description:	K562 cells expressing the RhD protein reacted strongly with the epitope-specific mAb. Mutation of the epitope containing region B resulted in severe reduction in mAb binding.

name:	iedb
homePage:	http://www.iedb.org

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