Human monoclonal immunoglobulin M antibodies to ganglioside GM1 show diverse cross-reactivities with lipopolysaccharides of Campylobacter jejuni strains associated with Guillain-Barré syndrome.

Title:

Human monoclonal immunoglobulin M antibodies to ganglioside GM1 show diverse cross-reactivities with lipopolysaccharides of Campylobacter jejuni strains associated with Guillain-Barré syndrome.

Dataset

identifier:	1827601
description:	epitope description:alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal antigen name:lipopolysaccharide host organism:Homo sapiens antibody name:SM 1-8
aggregation:	instance of dataset
availability:	available
primaryPublications:	10377164

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001256
landingPage:	http://www.iedb.org/assay/1827601

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	1999

Dimension

study type:	b cell assays
subject species:	Campylobacter jejuni subsp. jejuni 16971.94GSH (O:41)

Person

fullName:	M M Prendergast H J Willison A P Moran

Data Type

method:	western blot

Study

name:	Human monoclonal immunoglobulin M antibodies to ganglioside GM1 show diverse cross-reactivities with lipopolysaccharides of Campylobacter jejuni strains associated with Guillain-Barré syndrome.
description:	The epitope is deduced. The epitope-specific mAb is shown to cross-react with GM1 and C. jejuni LPS molecules derived from the O:41 serotype strains, such as 16971.94GSH, 28134.94GSH, 260.94RXH, 176.83 and the serostrain (serotype reference strain) O:41.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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