Fine specificity of antibodies against AQP4: epitope mapping reveals intracellular epitopes. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Fine specificity of antibodies against AQP4: epitope mapping reveals intracellular epitopes.

Dataset

identifier:	1830995
description:	epitope description:FCPDVEFKRRFKEAFSKAAQQTKG antigen name:Aquaporin-4 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	21333492

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022014
landingPage:	http://www.iedb.org/assay/1830995

Publication

type:	Literature
publicationVenue:	J Autoimmun
dates:	2011

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	E I Kampylafka J G Routsias H Alexopoulos M C Dalakas H M Moutsopoulos A G Tzioufas

Data Type

method:	antigen inhibition

Study

name:	Fine specificity of antibodies against AQP4: epitope mapping reveals intracellular epitopes.
description:	The epitope inhibited the binding of NMO sera to the epitope and to TAX1BP1 15-mer (EFKKRFSDATSKAHQ). Direct ELISA showed that 23.8% of the NMO sera reacted positively with the epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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