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identifier: 1831426
description:
epitope description:[8)-alpha-Neu5Pr-(2->]4
host organism:Mus musculus BALB/c
antibody name:10B9, 7C11, 11G1, 1F1, 11F3
aggregation:
instance of dataset
availability:
available
primaryPublications: 9166422
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1008163
landingPage: http://www.iedb.org/assay/1831426
type:
Literature
publicationVenue:
J Exp Med
dates:
1997
study type: b cell assays
subject species:
fullName:
R A Pon
M Lussier
Q L Yang
H J Jennings
method:
ELISA
name:
N-Propionylated group B meningococcal polysaccharide mimics a unique bactericidal capsular epitope in group B Neisseria meningitidis.
description:
The N-propylated alpha-2-8-sialic acid oligosaccharide is an analog of the acetylated species found as part of the capsular polysaccharide of N. meningiditis group B and of E. coli K1.
The mAbs obtained after immunization with the epitope were reactive with the (2-8)-NeuPr analog of the meningococcal polysaccharide. MAbs 10B9 and 7C11 are IgG1, mAb 11G1 is IgG2a, 1F1 is IgG2b and mAB 11F3 is IgG3.

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