HLA-DR alpha chain residues located on the outer loops are involved in nonpolymorphic and polymorphic antibody-binding epitopes.

Title:

HLA-DR alpha chain residues located on the outer loops are involved in nonpolymorphic and polymorphic antibody-binding epitopes.

identifier:	1834429
description:	epitope description:Q31 antigen name:HLA class II histocompatibility antigen, DR alpha chain host organism:Mus musculus BALB/c antibody name:I-2
aggregation:	instance of dataset
availability:	available
primaryPublications:	7520896

study type:	b cell assays
subject species:	Homo sapiens

fullName:	X T Fu R W Karr

method:	flow cytometry

name:	HLA-DR alpha chain residues located on the outer loops are involved in nonpolymorphic and polymorphic antibody-binding epitopes.
description:	The epitope-specific mAb bound to DRalpha. The residues comprising the epitope of the mAbs were determined by loss of binding to mutated DRalpha molecules. The mAbs bound to DRalpha in complex with ß1*0701 or I-Eß^k.

name:	iedb
homePage:	http://www.iedb.org

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