A strategy for rational design of fully synthetic glycopeptide conjugate vaccines. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

A strategy for rational design of fully synthetic glycopeptide conjugate vaccines.

Dataset

identifier:	1834464
description:	epitope description:VKGYLAGYLAGKGVDAGKLGTVSYG antigen name:Outer membrane protein P6 host organism:Oryctolagus cuniculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	9393776

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1011896
landingPage:	http://www.iedb.org/assay/1834464

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	1997

Dimension

study type:	b cell assays
subject species:	Haemophilus influenzae

Person

fullName:	P Chong N Chan A Kandil B O James Y P Yang S P Shi M Klein

Data Type

method:	ELISA

Study

name:	A strategy for rational design of fully synthetic glycopeptide conjugate vaccines.
description:	The peptide is known to contain T and B cell epitopes. The sequence has a duplication of residues YLAG that is not found in the current GenPept sequences. The antisera from mice immunized with the epitope alone or as part of a conjugate with the H. influenzae PRP3 oligosaccharide reacted with OMP P6. The epitope alone gave higher titers than the conjugate.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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