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identifier: 1834468
description:
epitope description:alpha-L-Fucp-(1->2)-alpha-L-Fucp-(1->3)-beta-D-GalpNAc-(1->4)-[alpha-L-Fucp-(1->2)-alpha-L-Fucp-(1->3)]-beta-D-GlcpNAc
antigen name:Gp18-22 Sm
host organism:Mus musculus BALB/c
antibody name:114-4D12
aggregation:
instance of dataset
availability:
available
primaryPublications: 17188765
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1007961
landingPage: http://www.iedb.org/assay/1834468
type:
Literature
publicationVenue:
Mol Biochem Parasitol
dates:
2007
study type: b cell assays
subject species: Schistosoma mansoni
fullName:
Marjolein L M Robijn
Carolien A M Koeleman
Manfred Wuhrer
Louise Royle
Rudolf Geyer
Raymond A Dwek
Pauline M Rudd
André
M Deelder
Cornelis H Hokke
method:
chromatography
name:
Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody.
description:
The epitope was described as derived from the O-glycan of the glycoprotein listed in Robijn et al, Mol Biochem Parasitol. (2007)151:148 [PMID:17188765].
An unconjugated oligosaccharide preparation could be purified by affinity chromatography with the epitope-specific mAB 114-4D12 from S. mansoni egg supernatant, Soluble Egg Antigen (SEA). The composition of the purified fractions, as analized by MALDI TOF-MS showed that they carry the epitope as the non-reducing end and differ in the reducing end extensions.