Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1016859 |
| landingPage: |
http://www.iedb.org/assay/1838756 |
| type: |
Literature
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| publicationVenue: |
Muscle Nerve
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| dates: |
2006
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| study type: | b cell assays |
| subject species: | Bos taurus |
| fullName: |
Xiao Mei Shu
Fang Cheng Cai
Xiao Ping Zhang
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| method: |
ELISA
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| name: |
Carbohydrate mimicry of Campylobacter jejuni lipooligosaccharide is critical for the induction of anti-GM1 antibody and neuropathy.
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| description: |
The ganglioside was obtained commercially. It is derived from bovine brain.
The presence of a GM1-like moiety on the lipooligosaccharide (LOS) of C. jejuni HB9313 is inferred by the ability of the antisera to generate anti-GM1 antibodies, while a galE mutant of the same strain fails to induce the anti-GM1 antibodies. Also, abnormality of sciatic-nerve teased fibers from animals sensitized with C. jejuni HB9313 was significantly higher than from animals immunized with the galE mutant.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
