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Title: Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site.
identifier: 1838725
description:
epitope description:LELDKWAS
antigen name:Envelope glycoprotein gp160
host organism:Homo sapiens
antibody name:2F5
aggregation:
instance of dataset
availability:
available
primaryPublications: 18824005
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1013909
landingPage: http://www.iedb.org/assay/1838725
type:
Literature
publicationVenue:
J Mol Biol
dates:
2008
study type: b cell assays
subject species: HIV-1 M:B
fullName:
Jean-Philippe Julien
Steve Bryson
Jose L Nieva
Emil F Pai
method:
x-ray crystallography
name:
Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site.
description:
The crystal structure of the epitope-specific Fab' 2F5 in complex with the longer peptide in the presence of ammonium sulfate was determined.

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