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Title: The monoclonal antibody TAL16.1 recognizes the aspartic acid residue at position 70 in DRB gene products.
identifier: 1839005
description:
epitope description:D99
antigen name:HLA class II histocompatibility antigen, DRB1-4 beta chain
host organism:Mus musculus C3H
antibody name:TAL16.1
aggregation:
instance of dataset
availability:
available
primaryPublications: 7681224
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1021031
landingPage: http://www.iedb.org/assay/1839005
type:
Literature
publicationVenue:
Tissue Antigens
dates:
1993
study type: b cell assays
subject species: Homo sapiens
fullName:
A M Sadler
J M Heyes
S G Marsh
P Krausa
G E Reynolds
J G Bodmer
method:
ELISA
name:
The monoclonal antibody TAL16.1 recognizes the aspartic acid residue at position 70 in DRB gene products.
description:
The epitope is located in the DRß
1*0402 molecule.
A comparison of the HLA-DRß amino acid sequences of reactive and non-reactive cells identified an aspartic acid residue at position 70, conserved in all antibody-positive cells and absent in antibody-negative cells, which was postulated as being responsible for conferring the specificity of the antibody.

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