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Title: A novel ICOS-independent, but CD28- and SAP-dependent, pathway of T cell-dependent, polysaccharide-specific humoral immunity in response to intact Streptococcus pneumoniae versus pneumococcal conjugate vaccine.
identifier: 1843215
description:
epitope description:phosphocholine
antigen name:teichoic acid
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 19050242
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016862
landingPage: http://www.iedb.org/assay/1843215
type:
Literature
publicationVenue:
J Immunol
dates:
2008
study type: b cell assays
subject species: Streptococcus pneumoniae type 14
fullName:
Quanyi Chen
Jennifer L Cannons
James C Paton
Hisaya Akiba
Pamela L Schwartzberg
Clifford M Snapper
method:
ELISA
name:
A novel ICOS-independent, but CD28- and SAP-dependent, pathway of T cell-dependent, polysaccharide-specific humoral immunity in response to intact Streptococcus pneumoniae versus pneumococcal conjugate vaccine.
description:
The Ab response to the epitope was reduced in SAP-/-, ICOS-/-, and CD28-/- mice.

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