Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis.

Title:

Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis.

Dataset

identifier:	1844844
description:	epitope description:GVYATRSSAVRLRSSV + CITR(R6, R11, R13) antigen name:Vimentin host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	21666230

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022216
landingPage:	http://www.iedb.org/assay/1844844

Publication

type:	Literature
publicationVenue:	Ann Rheum Dis
dates:	2011

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Hans Ulrich Scherer Diane van der Woude Annemiek Willemze Leendert A Trouw Rachel Knevel Silje W Syversen Michael P M van der Linden Benedicte Lie Tom W J Huizinga Dé siré e M F M van der Heijde Annette H M van der Helm-van Mil Tore K Kvien René E M Toes

Data Type

method:	ELISA

Study

name:	Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis.
description:	The epitope sequence was previously described in Vossenaar et al., Arthritis Res Ther:6(142) 2004 [PMID:15059278]. Serum reactivity to the epitope was significantly increased among shared-epitope-positive patients. Reactivity did not correlate with disease progression.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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