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Title: Heavy-chain complementarity-determining regions determine conformation selectivity of anti-abeta antibodies.
identifier: 1844904
description:
epitope description:DAEFGHDSGFEVRHQK
antigen name:Amyloid beta A4 protein
host organism:Mus musculus BALB/c
antibody name:mAb158, mAb1C3
aggregation:
instance of dataset
availability:
available
primaryPublications: 20714111
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1022263
landingPage: http://www.iedb.org/assay/1844904
type:
Literature
publicationVenue:
Neurodegener Dis
dates:
2011
study type: b cell assays
subject species: Mus musculus
fullName:
Dag Sehlin
Marie Hedlund
Anna Lord
Hillevi Englund
Pä
r Gellerfors
Staffan Paulie
Lars Lannfelt
Frida Ekholm Pettersson
method:
antigen inhibition
name:
Heavy-chain complementarity-determining regions determine conformation selectivity of anti-abeta antibodies.
description:
Aß42 protofibirls inhibited the binding of epitope-specific mAb to Aß42 protofibirls. The epitope-specific mAb also bound to Aß42 protofibrils in direct ELISA.

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