Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Structure of a core fragment of glycoprotein H from pseudorabies virus in complex with antibody. |
| identifier: | 1845995 |
| description: |
epitope description:V332, A333, P334, A335, Q337, P350, R351, D353, L354, R356, A357, T358, E361, A362, R365, K370, P371, F372, D373
antigen name:envelope glycoprotein H
host organism:Mus musculus
antibody name:A13-D6.3
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| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
21149698 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1022162 |
| landingPage: |
http://www.iedb.org/assay/1845995 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2010
|
| study type: | b cell assays |
| subject species: | Suid herpesvirus 1 strain Kaplan |
| fullName: |
Marija Backovic
Rebecca M DuBois
Joseph J Cockburn
Andrew J Sharff
Marie-Christine Vaney
Harald Granzow
Barbara G Klupp
Gerard Bricogne
Thomas C Mettenleiter
Felix A Rey
|
| method: |
x-ray crystallography
|
| name: |
Structure of a core fragment of glycoprotein H from pseudorabies virus in complex with antibody.
|
| description: |
The epitope of Fab A13-D6.3 on the core fragment of PrV envelope glycoportein H ectodomain was determined from the crystal structure. The disordered regions in the gHC structure are the N-terminal segment of 34 amino acids (107–130), five internal loops (198–210, 448–450, 469–482, 543–546, and 603–607) and the C-terminal five residues that connect to the TM region (634–639). There are two complexes in the asymmetric unit in which antigen-antibody contacts differ. Therefore they are curated as different assays.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |