The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia.

Title:

The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia.

identifier:	1849901
description:	epitope description:PAELMRRFELYF antigen name:DNA replication licensing factor MCM7 host organism:Mus musculus antibody name:2E6.7
aggregation:	instance of dataset
availability:	available
primaryPublications:	21601573

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Dorian Henderson Laura Hall Nikki Prpic Jan Hessling Margaret Parker Susan Sampson Stephen Simkins George Brough Eric Dixon Karen Lenz Steve Knapp Patricia Murphy Adriann Taylor Tim Fischer Douglas P Malinowski

method:	immuno staining

name:	The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia.
description:	The epitope-specific mAb reacted with abnormal cell nuclei in cervical squamous cell carcinoma (SCC), but not with negative for intraepithelial lesion and malignancy cytology samples. The epitope-specific mAb reactivity with cervical cytology cells increased dramatically along the course of disease (CIN I, CIN II and CIN III) and correlated with the pathology from the lesion.

name:	iedb
homePage:	http://www.iedb.org

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