Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1848128 |
| description: |
epitope description:I108, W111, V251, A277, S360, G361, G362, D363, E365, I366, S370, F377, Y379, K408, M413, E416, G460, D461, M462, R463
antigen name:Envelope glycoprotein gp160
host organism:Homo sapiens
antibody name:F105
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
19965434 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1022139 |
| landingPage: |
http://www.iedb.org/assay/1848128 |
| type: |
Literature
|
| publicationVenue: |
Science
|
| dates: |
2009
|
| study type: | b cell assays |
| subject species: | Human immunodeficiency virus type 1 (isolate YU2) |
| fullName: |
Lei Chen
Young Do Kwon
Tongqing Zhou
Xueling Wu
Sijy O'Dell
Lisa Cavacini
Ann J Hessell
Marie Pancera
Min Tang
Ling Xu
Zhi-Yong Yang
Mei-Yun Zhang
James Arthos
Dennis R Burton
Dimiter S Dimitrov
Gary J Nabel
Marshall R Posner
Joseph Sodroski
Richard Wyatt
John R Mascola
Peter D Kwong
|
| method: |
flow cytometry
|
| name: |
Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
|
| description: |
The epitope residues are calculated from the PDB structure [PDB: 3HI1] as the antigen residues at 4 Å
distance from the antibody.
The epitope-specific monoclonal antibody bound uncleaved gp160 on transfected 293T cells.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
