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identifier: 1848593
description:
epitope description:beta-D-GlcpA-(1->2)-alpha-D-Manp6Ac-(1->3)-[beta-D-Xylp-(1->2)]-alpha-D-Manp-(1->3)-[beta-D-Xylp-(1->2)]-alpha-D-Manp-(1->3)-alpha-D-Manp
antigen name:glucuronoxylomannan
host organism:Mus musculus BALB/c
antibody name:1H1
aggregation:
instance of dataset
availability:
available
primaryPublications: 19464529
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1014929
landingPage: http://www.iedb.org/assay/1848593
type:
Literature
publicationVenue:
Vaccine
dates:
2009
study type: b cell assays
subject species: Cryptococcus neoformans
fullName:
Antonio Nakouzi
Tong Zhang
Stefan Oscarson
Arturo Casadevall
method:
immuno staining
name:
The common Cryptococcus neoformans glucuronoxylomannan M2 motif elicits non-protective antibodies.
description:
The epitope is found in various proportions in GXM from the various C. neoformans serotypes. It is most common in serotype A GXM.
Immunofluorescence of the epitope-specific mAb with C. neoformans serotype D strain revealed a punctuate pattern. It failed to react with strains H99 (serotype A), NIH 3939 (serotype B) and NYS 1343 (serotype C).

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