| Title: | The common Cryptococcus neoformans glucuronoxylomannan M2 motif elicits non-protective antibodies. |
| identifier: | 1848593 |
| description: |
epitope description:beta-D-GlcpA-(1->2)-alpha-D-Manp6Ac-(1->3)-[beta-D-Xylp-(1->2)]-alpha-D-Manp-(1->3)-[beta-D-Xylp-(1->2)]-alpha-D-Manp-(1->3)-alpha-D-Manp
antigen name:glucuronoxylomannan
host organism:Mus musculus BALB/c
antibody name:1H1
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
19464529 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1014929 |
| landingPage: |
http://www.iedb.org/assay/1848593 |
| type: |
Literature
|
| publicationVenue: |
Vaccine
|
| dates: |
2009
|
| study type: | b cell assays |
| subject species: | Cryptococcus neoformans |
| fullName: |
Antonio Nakouzi
Tong Zhang
Stefan Oscarson
Arturo Casadevall
|
| method: |
immuno staining
|
| name: |
The common Cryptococcus neoformans glucuronoxylomannan M2 motif elicits non-protective antibodies.
|
| description: |
The epitope is found in various proportions in GXM from the various C. neoformans serotypes. It is most common in serotype A GXM.
Immunofluorescence of the epitope-specific mAb with C. neoformans serotype D strain revealed a punctuate pattern. It failed to react with strains H99 (serotype A), NIH 3939 (serotype B) and NYS 1343 (serotype C).
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |