Antigenically relevant amino acid positions as revealed by reactions of monoclonal antibodies with the nucleoproteins of closely related influenza A virus strains.

Title:

Antigenically relevant amino acid positions as revealed by reactions of monoclonal antibodies with the nucleoproteins of closely related influenza A virus strains.

Dataset

identifier:	1850196
description:	epitope description:V353 antigen name:Nucleoprotein host organism:Mus musculus BALB/c antibody name:Mab 7/3
aggregation:	instance of dataset
availability:	available
primaryPublications:	15503212

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/457
landingPage:	http://www.iedb.org/assay/1850196

Publication

type:	Literature
publicationVenue:	Arch Virol
dates:	2004

Dimension

study type:	b cell assays
subject species:	Influenza A virus (A/Puerto Rico/8/1934(Cambridge)(H1N1))

Person

fullName:	N L Varich N V Kaverin

Data Type

method:	immunoprecipitation

Study

name:	Antigenically relevant amino acid positions as revealed by reactions of monoclonal antibodies with the nucleoproteins of closely related influenza A virus strains.
description:	The epitope was deduced. The epitope was deduced by loss of recognition of nucleoproteins from influenza A virus strains with sequence difference. MAb 7/3 did not react with NP from strains PR/8/34-Mt.Sin, USSR/77 or Brazil/78 which have a substitution of L/I at position V353.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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