An exposed domain in the severe acute respiratory syndrome coronavirus spike protein induces neutralizing antibodies.

Title:

An exposed domain in the severe acute respiratory syndrome coronavirus spike protein induces neutralizing antibodies.

identifier:	1850697
description:	epitope description:STAIHADQLTPAWRIYSTGNN antigen name:Spike glycoprotein host organism:Mus musculus BALB/c antibody name:S78, S26
aggregation:	instance of dataset
availability:	available
primaryPublications:	15194798

study type:	b cell assays
subject species:	SARS coronavirus

fullName:	Tong Zhou Hong Wang Danlin Luo Thomas Rowe Zheng Wang Robert J Hogan Shihong Qiu Robert J Bunzel Guoqiang Huang Vinod Mishra Thomas G Voss Robert Kimberly Ming Luo

method:	ELISA

name:	An exposed domain in the severe acute respiratory syndrome coronavirus spike protein induces neutralizing antibodies.
description:	The epitope-specific mAb recognized whole cell lysates from Vero cells infected with SARS CoV (Toronto-2 isolate). Immunoprecipitation was also positive. MAb S26 also recognized the antigen in western blot. The epitope was deduced by N- and C-terminal truncation of the S-II fragment of the SARS spike protein.

name:	iedb
homePage:	http://www.iedb.org

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