| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1022225 |
| landingPage: |
http://www.iedb.org/assay/1851306 |
| type: |
Literature
|
| publicationVenue: |
J Hepatol
|
| dates: |
2011
|
| study type: | b cell assays |
| subject species: | Hepatitis B virus |
| fullName: |
Corinna M Bremer
Irina Sominskaya
Dace Skrastina
Paul Pumpens
Ahmed Abd El Wahed
Ulrike Beutling
Ronald Frank
Hans-Joachim Fritz
Gerhard Hunsmann
Wolfram H Gerlich
Dieter Glebe
|
| method: |
biological activity
|
| name: |
N-terminal myristoylation-dependent masking of neutralizing epitopes in the preS1 attachment site of hepatitis B virus.
|
| description: |
The epitope-specific antisera neutralized HBV, as measured in vitro by mixing with HBV and primary hepatocytes from Tupaia belangeri (Asian tree shrews). The read-out was the amount of newly produced HBsAg in the cell culture medium 12–15 days postinfection.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |