A common NH53K mutation in the combining site of antibodies raised against chlamydial LPS glycoconjugates significantly increases avidity.

Title:

A common NH53K mutation in the combining site of antibodies raised against chlamydial LPS glycoconjugates significantly increases avidity.

identifier:	1851752
description:	epitope description:alpha-D-Kdo-(2->8)-alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-beta-D-GlcNAc antigen name:lipopolysaccharide host organism:Mus musculus BALB/c antibody name:S25-39
aggregation:	instance of dataset
availability:	available
primaryPublications:	21405106

study type:	b cell assays
subject species:	Chlamydiae

fullName:	Ryan J Blackler Sven Mü ller-Loennies Cory L Brooks Dylan W Evans Lore Brade Paul Kosma Helmut Brade Stephen V Evans

method:	ELISA

name:	A common NH53K mutation in the combining site of antibodies raised against chlamydial LPS glycoconjugates significantly increases avidity.
description:	The mAb, which is specific for the family-specific Chlamydial epitope KDO-(2-8)-KDO-(2-4)-KDO, reacted also strongly with this longer tetrasaccharide-BSA conjugate in ELISA, with similar avidity than with the trisaccharide.

name:	iedb
homePage:	http://www.iedb.org

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