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Title: Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB).
identifier: 1852674
description:
epitope description:PCKSNT
antigen name:rRNA N-glycosidase (UniProt:B9T8T0)
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 21872634
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1022361
landingPage: http://www.iedb.org/assay/1852674
type:
Literature
publicationVenue:
Vaccine
dates:
2011
study type: b cell assays
subject species: Ricinus communis
fullName:
Anastasiya Yermakova
Nicholas J Mantis
method:
in vivo assay
name:
Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB).
description:
The author provided positions correspond to the location of the epitope on the Ricin Toxin subunit B. The epitope was deduced from homology to phage-displayed random peptides as described in the cited reference, McGuinness and Mantis, Infect Immun. 2006 74:3463 [PMID:16714577].
The epitope-specific mAb protected mice from ricin toxin challenge.

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