p185, an immunodominant epitope, is an autoantigen mimotope. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

p185, an immunodominant epitope, is an autoantigen mimotope.

Dataset

identifier:	1852752
description:	epitope description:PESFDGDPASNTAPLQPE antigen name:Receptor tyrosine-protein kinase erbB-2 host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	21566138

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022268
landingPage:	http://www.iedb.org/assay/1852752

Publication

type:	Literature
publicationVenue:	J Biol Chem
dates:	2011

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Sanjeev Kumar John A Hinks Joseph Maman Chelliah T Ravirajan Laurence H Pearl David A Isenberg

Data Type

method:	antigen inhibition

Study

name:	p185, an immunodominant epitope, is an autoantigen mimotope.
description:	Calf thymus dsDNA was able to inhibit binding of the epitope-specific antisera to the epitope. The antiera also bound dsDNA in direct binding ELISA. The mice also developed significant titers of IgG anti-ssDNA antibodies.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.