Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1853231 |
| description: |
epitope description:E22, L23, D25, D26, D27, M46, N48, L63, Y64, I139, H141, M170, T171, H172, G173, K174, T175, R176
antigen name:Interleukin-2 receptor subunit alpha
host organism:Mus musculus BALB/c
antibody name:daclizumab
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
20820193 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1022195 |
| landingPage: |
http://www.iedb.org/assay/1853231 |
| type: |
Literature
|
| publicationVenue: |
Cell Res
|
| dates: |
2010
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Hui Yang
Jianchuan Wang
Jiamu Du
Chen Zhong
Dapeng Zhang
Huaizu Guo
Yajun Guo
Jianping Ding
|
| method: |
x-ray crystallography
|
| name: |
Structural basis of immunosuppression by the therapeutic antibody daclizumab.
|
| description: |
The eptope of daclizumab on the IL-2Ralpha ectodomain was determined from the crystal structure of the complex, solved by molecular replacement. In the structure of the daclizumab Fab/IL-2Ralpha complex, there are two complexes in an asymmetric unit with almost identical overall structures.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
